|
A
|
Cumulative lifetime risk of developing adult T-cell leukemia or lymphoma (ATL) is 2%-5% among HTLV-I infected individuals.
|
|
|
B
|
HTLV-I, HTLV-II, HIV-I, and HIV-II all belong to the retroviral family.
|
|
|
C
|
HTLV-I was first isolated in 1980 from a T-cell lymphoma cell line from a patient originally thought to have cutaneous T-cell lymphoma.
|
|
|
D
|
The progressive spastic or ataxic myelopathy that develops in an individual who is HTLV-I-positive is most commonly due to leptomeningeal involvement.
|
|
|
E
|
HTLV-I is endemic in southwestern Japan and Okinawa, where more than 1 million persons are infected and antibodies to HTLV-I are present in the serum of up to 35% of Okinawans.
|
|